Asako S1, Ilies L, Nakamura E.
J Am Chem Soc. 2013 Nov 27;135(47):17755-7. doi: 10.1021/ja4106368. Epub 2013 Nov 13.Arenes possessing an N-(quinolin-8-yl)amide directing group are ortho-allylated with allyl phenyl ether in the presence of an iron/diphosphine catalyst and an organometallic base at 50-70 °C. The reaction proceeds via fast iron-catalyzed C-H activation, followed by reaction of the resulting iron intermediate with the allyl ether in γ-selective fashion.