CONTACT US

Email: info@alfa-chemistry.com
Tel:1-201-478-8534
1-516-662-5404
Fax: 1-516-927-0118
Address: Suite 212, Waverly Plaza, 755 Waverly Avenue, Holtsville, NY 11742, USA

For product inquiries, please use our online system or send an email to
inquiry@alfa-chemistry.com

chemistry partner
Home > Product > Organic Silicon Compounds > Other Organosilicon > 2-(Trimethylsilyl)acetic acid

2-(Trimethylsilyl)acetic acid | CAS Number: 2345-38-2

Catalog Number
ACM2345382
Product Name
2-(Trimethylsilyl)acetic acid
Structure
CAS Number
2345-38-2
EC Number
219-067-4
IUPAC Name
2-trimethylsilylaceticacid
Synonyms
me3SiCH2cox; 2-(Trimethylsilyl)acetic acid; 2-(Trimethylsilyl)ethansaeure; Trimethylsilylacetic acid; (trimethylsilyl)-aceticaci; trimethylsilanyl-acetic acid;
Category
Silicon hydrocarbyl carboxylic acids compounds
Molecular Weight
132.23
Exact Mass
132.06100
Molecular Formula
C5H12O2Si
Boiling Point
132.24ºC
Melting Point
39-42ºC
Flash Point
95ºC
Density
0.934g/cm3
Purity
95%+
Appearance
Transparent liquid
SMILES
C[Si](C)(C)CC(=O)O
InChIKey
JDMMZVAKMAONFU-UHFFFAOYSA-N
Safty Description
S26-S36
Hazard Statements
Xi:Irritant;
WGK Germany
2
Packing Group
III
If you have any other questions or need other size, please get a quote.
  • CAS
  • Size
  • Purity
  • Price
  • Availability
  • Quantity
  • Order
1Electroreductive Intermolecular Coupling of Coumarins with Benzophenones: Synthesis of 4-(2-Hydroxyphenyl)-5,5-diaryl-γ-butyrolactones, 2-(2,2-Diaryl-2,3-dihydrobenzofuran-3-yl)acetic Acids, and 4-(Diarylmethyl)coumarins.

Kise N1, Hamada Y1, Sakurai T1.

J Org Chem. 2016 Nov 18;81(22):11043-11056. Epub 2016 Oct 13.

The electroreductive coupling of coumarins with benzophenones in the presence of TMSCl gave adducts reacted at the 4-position of coumarins as trimethylsilyl ethers. From 3-methylcoumarin, 3,4-cis-adducts were formed stereoselectively. The de-trimethylsilylation of the adducts with 1 M HCl aq or TBAF in THF at 25 °C produced 4-(2-hydroxyphenyl)-5,5-diaryl-γ-butyrolactones. The γ-butyrolactones were further transformed to 2-(2,2-diaryl-2,3-dihydrobenzofuran-3-yl)acetic acids by treatment with 1 M HCl aq at reflux temperature. Read More

Share

Interested in our Services & Products ? Need detailed information?
facebook twitter linkedin google+

Contact us

Email:
Tel:1-201-478-8534
1-516-662-5404
Fax: 1-516-927-0118
Address: Suite 212, Waverly Plaza, 755 Waverly Avenue, Holtsville, NY 11742, USA