Zhang L1, Zhao X.
Org Lett. 2015 Jan 16;17(2):184-6. doi: 10.1021/ol5030986. Epub 2014 Dec 30.Transition-metal free heterocyclization reaction of 1,3-diynes with N,O-bis(trimethylsiyl)acetamide was accomplished in the presence of t-BuOK and acetonitrile at 120 °C. This method regioselectively gave 2,4,5-trisubstituted oxazoles in yields up to 97%.