Müller WE1, Schlossmacher U, Wang X, Boreiko A, Brandt D, Wolf SE, Tremel W, Schröder HC.
FEBS J. 2008 Jan;275(2):362-70. Epub 2007 Dec 13.Siliceous sponges can synthesize poly(silicate) for their spicules enzymatically using silicatein. We found that silicatein exists in silica-filled cell organelles (silicasomes) that transport the enzyme to the spicules. We show for the first time that recombinant silicatein acts as a silica polymerase and also as a silica esterase. The enzymatic polymerization/polycondensation of silicic acid follows a distinct course. Read More