CONTACT US

Email: info@alfa-chemistry.com
Tel:1-201-478-8534
1-516-662-5404
Fax: 1-516-927-0118
Address: Suite 212, Waverly Plaza, 755 Waverly Avenue, Holtsville, NY 11742, USA

For product inquiries, please use our online system or send an email to
inquiry@alfa-chemistry.com

chemistry partner
Home > Product > Material & Chemicals > Polymer/Macromolecule > 6-Maleimidocaproic acid

6-Maleimidocaproic acid | CAS Number: 55750-53-3

Catalog Number
ACM55750533
Product Name
6-Maleimidocaproic acid
Structure
CAS Number
55750-53-3
Synonyms
N-MALEOYL-6-AMINO-CAPROIC ACID;N-EPSILON-MALEIMIDOCAPROIC ACID;N-(5-CARBOXYPENTYL)MALEIMIDE;EMCA;EPSILON-MALEIMIDOCAPROIC ACID;6-MALEIMIDOCAPROIC ACID;6-MALEIMIDOHEXANOIC ACID;6-MALEIMIDOCAPROIC ACID, 98+%
Molecular Weight
211.21
Molecular Formula
C10H13NO4
If you have any other questions or need other size, please get a quote.
  • CAS
  • Size
  • Purity
  • Price
  • Availability
  • Quantity
  • Order
1Development of albumin-binding camptothecin prodrugs using a Peptide positional scanning library.

Schmid B1, Warnecke A, Fichtner I, Jung M, Kratz F.

Bioconjug Chem. 2007 Nov-Dec;18(6):1786-99. Epub 2007 Oct 5.

Designing truly tumor-specific prodrugs remains a challenge in the field of cancer chemotherapy. As a new strategy, we incubated homogenates of a spectrum of human colon tumor xenografts with a fluorogenic positional scanning tetrapeptide library in order to identify peptide sequences that are preferentially cleaved by colon tumors. Our screening experiments at pH 7.4 revealed that Met, Leu, and Lys were preferred amino acids in the position P(1) and Tyr, Phe, and Met in P(2), whereas in P(3) and P(4), the cleavage profiles were less characteristic. Read More

Share

Interested in our Services & Products ? Need detailed information?
facebook twitter linkedin google+

Contact us

Email:
Tel:1-201-478-8534
1-516-662-5404
Fax: 1-516-927-0118
Address: Suite 212, Waverly Plaza, 755 Waverly Avenue, Holtsville, NY 11742, USA