Petrova KT1, Potewar TM2, Correia-da-Silva P3, Barros MT2, Calhelha RC4, Ćiric A5, Soković M5, Ferreira IC4.
Carbohydr Res. 2015 Nov 19;417:66-71. doi: 10.1016/j.carres.2015.09.003. Epub 2015 Sep 15.A library of 1-(1',2,3,3',4,4',6-hepta-O-acetyl-6'-deoxy-sucros-6'-yl)-1,2,3-triazoles have been investigated for their antibacterial, antifungal and cytotoxic activities. Most of the target compounds showed good inhibitory activity against a variety of clinically and food contaminant important microbial pathogens. In particular, 1-(1',2,3,3',4,4',6-hepta-O-acetyl-6'-deoxy-sucros-6'-yl)-4-(4-pentylphenyl)-1,2,3-triazole (5) was highly active against all the tested bacteria with minimal inhibitory concentrations (MICs) ranging between 1. Read More