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Home > Product > Material & Chemicals > Polymer/Macromolecule > 4-Chloro-6-methyl-m-phenylene diisocyanate

4-Chloro-6-methyl-m-phenylene diisocyanate | CAS Number: 15166-26-4

Catalog Number
ACM15166264
Product Name
4-Chloro-6-methyl-m-phenylene diisocyanate
Structure
CAS Number
15166-26-4
Synonyms
4-CHLORO-6-METHYL-1,3-PHENYLENE DIISOCYANATE;4-CHLORO-6-METHYL-M-PHENYLENE DIISOCYANATE;5-CHLORO-2,4-TOLUENE DIISOCYANATE;4-Chloro-6-methyl-m-phenylenebisisocyanate
Molecular Weight
208.6
Molecular Formula
C9H5ClN2O2
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1Potential Inhibitory Influence of miRNA 210 on Regulatory T Cells during Epicutaneous Chemical Sensitization.

Long CM1,2, Lukomska E3, Marshall NB4, Nayak A5, Anderson SE6.

Genes (Basel). 2016 Dec 27;8(1). pii: E9. doi: 10.3390/genes8010009.

Toluene diisocyanate (TDI) is a potent low molecular weight chemical sensitizer and a leading cause of chemical-induced occupational asthma. The regulatory potential of microRNAs (miRNAs) has been recognized in a variety of disease states, including allergic disease; however, the roles of miRNAs in chemical sensitization are largely unknown. In a previous work, increased expression of multiple miRNAs during TDI sensitization was observed and several putative mRNA targets identified for these miRNAs were directly related to regulatory T-cell (Treg) differentiation and function including Foxp3 and Runx3. Read More

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