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Home > Product > Material & Chemicals > Micro/NanoElectronics > 4,4-(1,3-Adamantanediyl)diphenol

4,4-(1,3-Adamantanediyl)diphenol | CAS Number: 37677-93-3

Catalog Number
ACM37677933
Product Name
4,4-(1,3-Adamantanediyl)diphenol
Structure
CAS Number
37677-93-3
Synonyms
4,4-(1,3-ADAMANTANEDIYL)DIPHENOL;4,4-(1,3-AdaMantanediyl)bisphenol;1,3-Bis(4-Hydroxyphenyl)AdaMantane;1,3-Bis(p-hydroxyphenyl)adamantane;Adamantate
Molecular Weight
320.42
Molecular Formula
C22H24O2
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1Interactions of synthetic estrogens with human estrogen receptors.

Nikov GN1, Eshete M, Rajnarayanan RV, Alworth WL.

J Endocrinol. 2001 Jul;170(1):137-45.

Synthetic estrogens have diverse chemical structures and may either positively or negatively affect the estrogenic signaling pathways through interactions with the estrogen receptors (ERs). Modeling studies suggest that 4-(1-adamantyl)phenol (AdP) and 4,4'-(1,3-adamantanediyl)diphenol (AdDP) can bind in the ligand binding site of ERalpha. We used fluorescence polarization (FP) to compare the binding affinities of AdP, AdDP and 2-(1-adamantyl)-4-methylphenol (AdMP) for human ERalpha and ERbeta with the binding affinities of the known ER ligands, diethylstilbestrol (DES) and 4hydroxytamoxifen (4OHT). Read More

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Tel:1-201-478-8534
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