Bazanella Sampaio T1, da Rocha JT2, Brandão Quines C1, Agnes Stein AL1, Zeni G1, Nogueira CW3.
J Cell Biochem. 2016 Sep 15. doi: 10.1002/jcb.25740. [Epub ahead of print]Organoselenium compounds and isoquinoline derivatives have their toxicity linked to induction of pro-oxidant situations. δ-Aminolevulinate dehydratase (δ-ALA-D) and Na+ , K+ -ATPase have sulfhydryl groups susceptible to oxidation. Thus, we investigated toxicological effects of 4-organoseleno-isoquinoline derivatives, cerebral monoamine oxidase B inhibitors, on rat cerebral δ-ALA-D and Na+ , K+ -ATPase activities and the involvement of sulfhydryl groups in vitro. Read More