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Home > Product > Material & Chemicals > Polymer/Macromolecule > 3,3-Dimethylglutaric anhydride

3,3-Dimethylglutaric anhydride | CAS Number: 4160-82-1

Catalog Number
ACM4160821
Product Name
3,3-Dimethylglutaric anhydride
Structure
CAS Number
4160-82-1
EC Number
223-998-1
IUPAC Name
4,4-dimethyloxane-2,6-dione
Synonyms
3,3-DIMETHYL GLUTARIC ANHYDRIDE;3,3-DIMETHYLGLUTARIC ANHYDRIDE;BETA-BETA-DIMETHYLGLUTARIC ANHYDRIDE;3,3-Dimethyladipic anhydride;4,4-Dimethyldihydro-2H-pyran-2,6(3H)-dione;dihydro-4,4-dimethyl-2h-pyran-6(3h)-dione;Glutaric anhydride, 3,3-dimethyl-;Glutari
Molecular Weight
142.15
Exact Mass
142.06300
Molecular Formula
C7H10O3
Boiling Point
181ºC(25 torr)
Melting Point
122-126ºC
Flash Point
181°C/25mm
Density
1.102g/cm3
Purity
96%
Appearance
White to off-white crystalline powder
SMILES
CC1(CC(=O)OC(=O)C1)C
InChIKey
HIJQFTSZBHDYKW-UHFFFAOYSA-N
H-Bond Donor
0
H-Bond Acceptor
3
Safty Description
S24/25
Hazard Statements
Xi:Irritant;
WGK Germany
3
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1Structure and function of anhydride-modified forms of human insulin: In silico, in vitro and in vivo studies.

Chinisaz M1, Ebrahim-Habibi A2, Dehpour AR3, Yaghmaei P4, Parivar K4, Moosavi-Movahedi AA5.

Eur J Pharm Sci. 2017 Jan 1;96:342-350. doi: 10.1016/j.ejps.2016.09.030. Epub 2016 Sep 27.

Insulin is a therapeutic protein whose amyloid formation is reported in diabetic patients. Four anhydride compounds were used in the current study in order to experiment their potential reducing effect on insulin propensity to form amyloid fibrils. The modified forms (obtained with succinic-, 3,3-dimethylglutaric, 2-phenylglutaric-, and (2-Dodecen-1-yl) succinic anhydride), were first characterized with regard to melting temperature (Tm), changes in secondary structure percentage and hydrophobic surface. Read More

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Tel:1-201-478-8534
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