Byrne N1, Hayes-Larson E, Liao WW, Kraml CM.
J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Nov 1;875(1):237-42. doi: 10.1016/j.jchromb.2008.06.057.2,2,2-Trifluoroethanol (TFE) is evaluated as an alternative modifier for the analysis and purification of alcohol-sensitive chiral compounds using supercritical fluid chromatography (SFC). Four chiral compounds, selected for their sensitivity to alcohols, in addition to a variety of standard chiral compounds were analyzed by SFC using TFE with polysaccharide and Pirkle-type chiral stationary phases (CSPs) to produce selectivities (alpha) and resolutions (Rs) as high as 1. Read More