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2,6-Diaminopurine | CAS Number: 1904-98-9

Catalog Number
ACM1904989
Product Name
2,6-Diaminopurine
Structure
CAS Number
1904-98-9
Synonyms
PYRIDINE-2,6-DIAMINE;TIMTEC-BB SBB004340;TIMTEC-BB SBB000103;2,6-DIAMINOPURINE;2,6-DIAMINO-9H-PURINE;26DAPY;1H-PURINE-2,6-DIAMINE;9H-PURINE-2,6-DIAMINE
Molecular Weight
150.14
Molecular Formula
C5H6N6
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1Continuous Fluorescence Assays for Reactions Involving Adenine.

Firestone RS1, Cameron SA1, Tyler PC2, Ducati RG1, Spitz AZ1, Schramm VL1.

Anal Chem. 2016 Dec 6;88(23):11860-11867. Epub 2016 Nov 11.

5'-Methylthioadenosine phosphorylase (MTAP) and 5'-methylthioadenosine nucleosidase (MTAN) catalyze the phosphorolysis and hydrolysis of 5'-methylthioadenosine (MTA), respectively. Both enzymes have low KM values for their substrates. Kinetic assays for these enzymes are challenging, as the ultraviolet absorbance spectra for reactant MTA and product adenine are similar. We report a new assay using 2-amino-5'-methylthioadenosine (2AMTA) as an alternative substrate for MTAP and MTAN enzymes. Read More

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Email:
Tel:1-201-478-8534
1-516-662-5404
Fax: 1-516-927-0118
Address: Suite 212, Waverly Plaza, 755 Waverly Avenue, Holtsville, NY 11742, USA