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Home > Product > Material & Chemicals > Organic & Printed Electronics > 2,5-Dibromo-3-hexylthiophene

2,5-Dibromo-3-hexylthiophene | CAS Number: 116971-11-0

Catalog Number
ACM116971110
Product Name
2,5-Dibromo-3-hexylthiophene
Structure
CAS Number
116971-11-0
Synonyms
2,5-DIBROMO-3-HEXYLTHIOPHENE;2,5-Dibromo-3-hexylt;3-BroMo-N-phenylcarbazole/3-BroMo-9-phenylcarbazole;DibroMo-3-hexylthioph;Thiophene,2,5-dibroMo-3-hexyl-;2,5-Dibromo-3-hexylthiophene 97%
Molecular Weight
326.09
Molecular Formula
C10H14Br2S
Purity
>97.0%(GC)
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1Efficient Double Suzuki Cross-Coupling Reactions of 2,5-Dibromo-3-hexylthiophene: Anti-Tumor, Haemolytic, Anti-Thrombolytic and Biofilm Inhibition Studies.

Ikram HM1, Rasool N2, Zubair M3, Khan KM4, Abbas Chotana G5, Akhtar MN6, Abu N7, Alitheen NB8, Elgorban AM9, Rana UA10.

Molecules. 2016 Jul 27;21(8). pii: E977. doi: 10.3390/molecules21080977.

The present study describes several novel 2,5-biaryl-3-hexylthiophene derivatives (3a-i) synthesized via a Pd(0)-catalyzed Suzuki cross-coupling reaction in moderate to good yields. The novel compounds were also analyzed for their anti-thrombolytic, haemolytic, and biofilm inhibition activities. In addition, the anti-tumor activity was also evaluated in vitro for newly-synthesized compounds, where 3-hexyl-2,5-bis(4-(methylthio)phenyl)thiophene exhibited the best anti-tumor activity against 4T1 cells with IC50 value of 16 μM. Read More

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Address: Suite 212, Waverly Plaza, 755 Waverly Avenue, Holtsville, NY 11742, USA