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Home > Product > Material & Chemicals > Organic & Printed Electronics > 2,5‐Bis(trimethylstannyl)thiophene

2,5‐Bis(trimethylstannyl)thiophene | CAS Number: 86134-26-1

Catalog Number
ACM86134261
Product Name
2,5‐Bis(trimethylstannyl)thiophene
Structure
CAS Number
86134-26-1
IUPAC Name
trimethyl-(5-trimethylstannylthiophen-2-yl)stannane
Synonyms
2,5‐ bis(triMethylstannyl)th iophene;Stannane, 1,1-(2,5-thiophenediyl)bis[1,1,1-triMethyl- Stannane, 2,5-thiophenediylbis[triMethyl- (9CI);2,5-Bis(triMethylstannyl)thiophene 97%;1,1′-(2,5-thiophenediyl)bis[1,1,1-trimethyl] Stannane
Molecular Weight
409.7508
Exact Mass
411.93300
Molecular Formula
C10H20SSn2
Purity
96%
SMILES
C[Sn](C)(C)C1=CC=C(S1)[Sn](C)(C)C
InChIKey
KKRPPVXJVZKJON-UHFFFAOYSA-N
H-Bond Donor
0
H-Bond Acceptor
1
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1Synthesis and antiparasitic evaluation of bis-2,5-[4-guanidinophenyl]thiophenes.

Gonzalez JL1, Stephens CE, Wenzler T, Brun R, Tanious FA, Wilson WD, Barszcz T, Werbovetz KA, Boykin DW.

Eur J Med Chem. 2007 Apr;42(4):552-7. Epub 2006 Nov 22.

A series of bis-2,5-[4-guanidinophenyl]thiophenes were prepared in a five step process starting from 2,5-bis[trimethylstannyl]thiophene. The compounds were evaluated in vitro against Trypanosoma brucei rhodesiense (T. b. r.), Plasmodium falciparum (P. f.), Leshmania donovani (L. d.) and Trypanasoma cruzi (T. c.), and in vivo against T. b. r. Certain compounds show promising in vitro activity against T. b. r. and P. f. and have superior in vivo activity against T. b. r. to that of pentamidine and furamidine.

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Tel:1-201-478-8534
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