Li Y1, Tian R1, Zheng X2, Huang R3.
Anal Chim Acta. 2016 Aug 31;934:59-65. doi: 10.1016/j.aca.2016.06.035. Epub 2016 Jun 28.The common drawback of optical methods for rapid detection of nucleic acid by exploiting the differential affinity of single-/double-stranded nucleic acids for unmodified gold nanoparticles (AuNPs) is its relatively low sensitivity. In this article, on the basis of selective preconcentration of AuNPs unprotected by single-stranded DNA (ssDNA) binding, a novel electrochemical strategy for nucleic acid sequence identification assay has been developed. Read More