Simone P1, Pierri G1, Capitani D2, Ciogli A1, Angelini G2, Ursini O2, Gentile G3, Cavazzini A4, Villani C1, Gasparrini F5.
J Chromatogr A. 2016 Nov 23. pii: S0021-9673(16)31551-5. doi: 10.1016/j.chroma.2016.11.039. [Epub ahead of print]Capillary methacrylate-based monoliths were prepared for the high performance liquid chromatography (HPLC) separation of both small molecules and large biomolecules. An efficient grafting from/to synthetic approach was adopted introducing a network of activated sites in the inner wall surface using the new silanization agent (N-trimethoxysilylpropyl)-polyethylenimine. Copolymerization of lauryl methacrylate monomer and 1,6-hexanediol dimethacrylate cross-linker in the presence of porogenic solvents was obtained under continuous γ-ray exposure with high conversion yield. Read More