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Home > Product > Material & Chemicals > Polymer/Macromolecule > 1,4-Bis(aminomethyl)benzene

1,4-Bis(aminomethyl)benzene | CAS Number: 539-48-0

Catalog Number
ACM539480
Product Name
1,4-Bis(aminomethyl)benzene
Structure
CAS Number
539-48-0
Synonyms
1,4-BIS(AMINOMETHYL)-BENZENE;1,4-BIS(AMINOMETHYL)XYLENE;ALPHA,ALPHA-DIAMINO-P-XYLENE;P-XYLYLENEDIAMINE;P-XYLYLENE-ALPHA,ALPHA-DIAMINE;P-XYLENE DIAMINE;RARECHEM AL BW 0024;1,4-Benzenedimethanamine
Molecular Weight
136.19
Molecular Formula
C8H12N2
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1Synthesis of a versatile building block combining cyclen-derivative DO3A with a polyamine via a rigid spacer.

Drahoš B1, Trávníček Z.

Molecules. 2013 Nov 12;18(11):13940-56. doi: 10.3390/molecules181113940.

The five-step synthesis of a polydentate building block combining a cyclen-based macrocycle (DO3A) with N-(2-aminoethyl)propane-1,3-diamine, which are linked through the xylylen moiety as a rigid C-spacer is described. These two molecular parts were coupled by subsequent bromine atom substitution in 1,4-bis(bromomethyl)benzene. First, N-(2-aminoethyl)propane-1,3-diamine was protected by phthaloyl moieties and then it was reacted with 1,4-bis(bromomethyl)benzene to form (2-phthalimidoethyl)(3-phthalimido-prop-1-yl)(4-bromomethylbenzyl)amine (2). Read More

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