Rahman MS1, Thomas P2.
Comp Biochem Physiol A Mol Integr Physiol. 2015 Jul;185:91-106. doi: 10.1016/j.cbpa.2015.03.013. Epub 2015 Apr 2.Neuronal nitric oxide synthase (nNOS) catalyzes production of nitric oxide in vertebrate brains. Recent findings indicate that endothelial NOS and reactive oxygen species (ROS) are significantly increased during hypoxic stress and are modulated by antioxidants. However, the influence of antioxidants and steroids on nNOS upregulation by hypoxia is largely unknown. In this study, we characterized nNOS cDNA and examined the effects of hypoxia and antioxidant and steroid treatments on nNOS expression in Atlantic croaker hypothalamus. Read More