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Home > Product > Material & Chemicals > Biomaterials > 1,3-Dimercaptopropane

1,3-Dimercaptopropane | CAS Number: 109-80-8

Catalog Number
ACM109808
Product Name
1,3-Dimercaptopropane
Structure
CAS Number
109-80-8
Synonyms
1,3-Propanedimercaptan;1,3-propyldimercaptan;NDR-132;FEMA 3588;DITHIOTRIMETHYLENEGLYCOL;1,3-DIMERCAPTOPROPANE;1,3-PROPANEDITHIOL;propane-1,3-dithiol
Molecular Weight
108.23
Molecular Formula
C3H8S2
Purity
>95.0%(T)
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1Contribution of dithiol ligands to in vitro and in vivo trypanocidal activities of dithiaarsanes and investigation of ligand exchange in an aqueous solution.

Loiseau PM1, Lubert P, Wolf JG.

Antimicrob Agents Chemother. 2000 Nov;44(11):2954-61.

Twelve new dithiaarsanes were evaluated for their in vitro and in vivo trypanocidal properties in regard to their three parent molecules, 4-amino-phenylarsenoxide, melarsenoxide, and 4-dansylamino-phenylarsenoxide. The most potent dithiaarsane, compound 2b, had a minimum effective concentration of 1.5 nM after 48 h of incubation and at a dose of 0.39 micromol/kg of body weight (0.2 mg/kg) administered subcutaneously cured 100% of mice acutely infected with Trypanosoma brucei brucei CMP. Read More

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