Júnior CO1, le Hyaric M, Costa CF, Corrêa TA, Taveira AF, Araújo DP, Reis EF, Lourenço MC, Vicente FR, Almeida MV.
Mem Inst Oswaldo Cruz. 2009 Aug;104(5):703-5.A series of diamines and amino alcohols derived from 1-dodecanol, 1-tetradecanol, 1,2-dodecanediol and 1,2-tetradecanediol were synthesized and tested for their antitubercular activity. Compounds 3, 8 and 9 were found to be the most active (MIC of 6.25 microg/mL). Nine other compounds displayed activity against Mycobacterium tuberculosis, with a MIC of 12.5 microg/mL.